Anti‑aging and biostimulatory
Advanced Anti-Aging with Biostimulators
In addition to traditional fillers, our non‑surgical anti‑aging protocols use biostimulators that prompt your skin to regenerate collagen, elastin and extracellular matrix for long‑term rejuvenation.
Polynucleotides (PDRN)
Key indications:
- Stimulates skin repair and collagen production, leading to firmer, more elastic skin
- Improves hydration and texture, reducing fine lines and supporting wound healing or scar revision
Polynucleotides, often marketed as PDRN or salmon DNA, consist of DNA fragments extracted from salmon sperm or testes. Dermatologists note that PDRN binds to specific cellular receptors, stimulating skin cell turnover, supporting tissue repair and reducing inflammation . These injections promote fibroblast activity, leading to firmer skin, improved elasticity and increased moisture retention Treatments such as Rejuran and Nucleofill deliver PDRN directly into the dermis for targeted repair. Topical PDRN products may provide surface hydration but lack the depth of injectables Possible side effects include temporary redness, swelling or bruising; therefore proper technique and professional guidance are essential.
Poly‑L‑lactic acid (PLLA) injectables
Key indications:
- Gradual volumisation and collagen stimulation to address deeper wrinkles and volume loss
- FDA‑approved for treatment of facial lipoatrophy and deep facial folds; also used for buttock and hip augmentation
- Results last over two years, typically requiring a series of treatments for optimal outcomes
Sculptra and Lanluma are PLLA‑based biostimulators. Rather than providing instant volume, they work by stimulating your own collagen production. After injection, the poly‑L‑lactic acid microparticles are gradually absorbed, prompting fibroblasts to synthesise new collagen Results develop over 4–6 weeks and can last more than two years Sculptra is FDA‑approved for reducing deep wrinkles and for treating lipoatrophy; it is commonly injected in the buttocks or hips to restore volume. Because the outcome is gradual, patients often require a series of treatments but enjoy natural‑looking, long‑lasting improvements.
Calcium‑ hydroxylapatite (CaHA) biostimulator
Key indications:
- Provides immediate lift and volume with longer‑term collagen stimulation for sustained results.
- Ideal for deeper facial folds, jawline contouring and hand rejuvenation.
Radiesse is an injectable filler composed of tiny CaHA microspheres suspended in a gel carrier. The gel provides an immediate lifting and volumising effect; meanwhile the CaHA particles act as a scaffold beneath the skin. As the gel is absorbed, fibroblasts are drawn to the CaHA microspheres, triggering neocollagenesis; the new collagen gradually replaces the gel, creating a long‑term foundation for restored volume and improved skin structure. CaHA is a mineral naturally found in human bone, which makes Radiesse highly biocompatible. This dual‑action filler yields both immediate and lasting results and is ideal for deeper facial folds, jawline contouring or hand rejuvenation.
Hyaluronic‑ acid–amino‑acid boosters
Key indications (Sunekos):
- Hydrates and stimulates collagen and elastin to improve elasticity and skin texture.
- Suitable for dark circles, fine lines and skin laxity on the face, neck, décolleté, hands and body, with minimal downtime.
Key indications (Jalupro)
- Biorevitalises body skin and aids scar treatment by combining amino acids with low‑molecular‑weight HA.
- Provides hydration and stimulates collagen in the face, neck and hands using higher‑molecular‑weight HA.
Jalupro is another amino‑acid–rich injectable that delivers “collagen building blocks.” The Classic formulation is indicated for body skin biorevitalisation and scar treatment and combines amino acids with low‑molecular‑weight HA. Jalupro HMW uses a higher‑molecular‑weight HA to provide hydration and combines an amino‑acid cluster to increase collagen production, making it ideal for the face, neck and hands. These products support tissue regeneration and improve skin structure while maintaining a natural appearance.
Our practice in Dubai offers bespoke non‑surgical facial and body rejuvenation using a range of neuromodulators, reversible fillers and biostimulators. By understanding how each product works and the indications, we tailor treatments to your anatomy, lifestyle and goals. Safety and patient education are paramount — we use only FDA‑approved or CE‑marked injectables, avoid permanent fillers and emphasise proper aftercare. Book a consultation to discuss which neurotoxin, filler or biostimulatory treatment is right for you.
Anti-Aging & Biostimulatory Frequently Asked Questions
1. What are biostimulatory treatments?
Biostimulatory treatments use injectable substances that stimulate your skin to produce its own collagen, elastin and extracellular matrix. They help restore firmness, improve texture and deliver long-lasting anti-aging results.
2. How are biostimulators different from traditional fillers?
Traditional fillers provide instant volume. Biostimulators workgradually by activating fibroblasts to rebuild collagen and skin structure from within, leading to more natural and longer-lasting rejuvenation.
3. What are polynucleotides (PDRN)?
Polynucleotides are chains of DNA fragments extracted primarily from salmon. They enhance skin repair, reduce inflammation and boost collagen production.
4. How soon can I see results from PDRN?
Most patients notice improved texture and hydration within 2–3 weeks, with continued improvement over several sessions.
5. What is PLLA and how does it work?
Poly-L-lactic acid is a collagen-stimulating injectable. After it is injected, the microparticles slowly activate fibroblasts to produce new collagen, restoring lost volume over time.
6. How long do PLLA results last?
Results typically appear within 4–6 weeks and can last more than two years, making it one of the longest-lasting collagen stimulators.
7. What is CaHA and where is it used?
CaHA (used in Radiesse®) contains calcium-based microspheres in a gel. It provides immediate lift while stimulating collagen over time. It is ideal for jawline contouring, deeper folds and hand rejuvenation.
8. How is CaHA different from other biostimulators?
It delivers both instant volume and long-term collagen stimulation. Additionally, CaHA is highly biocompatible because it resembles natural minerals found in human bone.
9. What are HA–amino-acid skin boosters?
These injectables combine hyaluronic acid with amino acids — the building blocks of collagen. They hydrate, repair and rejuvenate thin or aging skin.
10. Are biostimulatory treatments safe?
Yes — when performed by trained medical professionals. Side effects are typically mild (redness, swelling or bruising). Your clinic prioritises FDA-approved/CE-marked products, safe injection techniques and comprehensive aftercare.